Umbilical cord blood gas analysis has for many years been recommended for assessment of newborn babies after high-risk delivery associated with possible hypoxic stress and consequent risk of permanent brain damage. More recently there has been an increasing trend towards its routine use after all deliveries.  With...

Increased serum bilirubin (hyperbilirubinemia) and consequent jaundice are common during the neonatal period. Around 50 % of newborns develop some degree of jaundice, during the first week of life, but for the vast majority this is mild (serum bilirubin peaking no higher than 150-200 µmol/L) and spontaneously resolves ...

Part 2: Red flags The transition from fetus to newborn is a process of rapid physiological adaptation that is sometimes delayed by complications. Most newborns complete the process of transition with little or no delay.  These infants may demonstrate normal transitional findings, including tachypnea and tachycardia, ...

Part 1: The physiology of transition The transition from fetus to neonate is a critical time of physiological adaptation. While the majority of term infants complete this process in a smooth and organized fashion, some infants experience a delay in transition or exhibit symptoms of underlying disease. Careful...

Reprinted and translated by permission of Danske Bioanalytikere, dbio from "Fra hæl eller håndryg", by Jytte Kristensen, dbio, vol no 4, 2007, pp 8-11. Copyright 2007 by dbio. Translated by Radiometer Medical ApS. Norwegian and Danish biomedical laboratory scientists disagree on best practice when collecting blood...

Modern blood gas analyzers often have incorporated technology that allows hemoglobin measurement on the same blood sample used to measure pH, pCO₂ and pO₂. Clinicians working in a UK neonatal intensive care department where such an instrument was routinely used for blood gases were keen to exploit the newly available...

Blood gas analysis of umbilical cord blood provides the means for establishing the acid-base status of babies at the time of birth. If there is to be any delay in sampling, the portion of cord from which the sample is to be taken should be double-clamped and thereby isolated from the placenta.  Previous studies have...

Where do you go for help, when you are a parent of a child who stops breathing while it sleeps? If you live in the south of Sweden, you go to Halmstad County Hospital, where a team of specialists are ready to monitor your sleeping child by polysomnography (PSG). The neonatal intensive care unit (NICU) in Halmstad has ...

Reduced blood glucose (hypoglycemia) is one of the more common metabolic emergencies during the neonatal period, which in a small minority of cases results in permanent brain damage. It remains unclear how low blood glucose concentration must fall for such devastating effect. This gray area of understanding is...

Pulse oximetry provides the means for continuous non-invasive monitoring of oxygen saturation (SpO₂). Although not currently used for the purpose, recent international guidelines suggest that pulse oximetry may be useful in the assessment of newborns who require urgent resuscitative measures at the time of birth....