There are few medical diagnoses that depend solely on the result of a single blood test, but diabetes mellitus, which is defined by concentration of circulating glucose, is one that does. Quite apart from its long established role in diagnosis as well as life-long monitoring of diabetes, measurement of circulating...

Tartu University Hospital has improved the quality of blood gas testing in its clinical laboratory and critical care units by introducing an automatic system for blood gas analysis. Not only did the quality of processes in the preanalytical phase improve, but also the automatic calculation of pO₂(A-a), for APACHE...

The integrity and function of all cells depend on an adequate supply of oxygen. Severe acute illness is frequently associated with inadequate tissue perfusion and/or reduced amount of oxygen in blood (hypoxemia) leading to tissue hypoxia.  If not reversed, tissue hypoxia can rapidly progress to multiorgan failure and ...

Part 2: Red flags The transition from fetus to newborn is a process of rapid physiological adaptation that is sometimes delayed by complications. Most newborns complete the process of transition with little or no delay.  These infants may demonstrate normal transitional findings, including tachypnea and tachycardia, ...

Tartu University Hospital has improved the quality of blood gas testing in its clinical laboratory and critical care units by introducing an automatic system for blood gas analysis [1].

Part 1: The physiology of transition The transition from fetus to neonate is a critical time of physiological adaptation. While the majority of term infants complete this process in a smooth and organized fashion, some infants experience a delay in transition or exhibit symptoms of underlying disease. Careful...

Homeostatic mechanisms ensure that in health the extracellular fluid (ECF) concentration of electrolytes, including calcium, is maintained within well-defined limits. Abnormality in ECF calcium concentration can have profound adverse effects.  The most common means of assessing calcium status is to measure total...

In most hospitals, the amount of nursing time spent on actual patient care is only 33 %, while problem solving consumes 40 % of their time. That’s the bad news. The good news is that inverting this ratio may be easier than you think.  According to Dr John Kenagy and David Sundahl of the US-based Kenagy & Associates,...

Blood gas analysis is a complex field that has a direct impact on patient care in a critical care environment. Healthcare professionals consistently emphasize high-quality results in order to properly treat patients, and recognize the need and usefulness of quality standards.  Using a path-of-workflow analysis as part ...

The significance of good practice during the pretesting phase of clinical laboratory investigation cannot be  overemphasized. The production of high-quality, accurate results which are clinically useful depends as much on practice before the patient’s sample reaches the laboratory as it does on the analytical phase...