Preanalytical errors are said to be the reason for up to 75 % [1] of all errors in laboratory medicine. The diagnostic consequences depend on the magnitude of the preanalytical error.  In worst case, these errors may lead to mistreatment of patients; in all cases, these errors are an extra workload for the hospital...

England's Oxford Radcliffe Hospitals have a POCT system they consider a success. This is a roadmap of the steps they have taken.

According to the Hvidovre Hospital, standardizing is a must if POCT is to run optimally. In the first article of the series "POCT setups for blood gas", acutecaretesting.org interviews the Danish hospital on how they have successfully implemented POCT.

When performing method comparisons, it is important to address a number of preparatory and preanalytical issues to ensure that comparisons solely reflect the analytical differences between the two methods in question. This article provides preparatory and preanalytical checklists that can be used when comparing two...

The measurement of the electrolytes in blood is one of the most frequently performed measurements as the electrolytes are of major physiological importance for numerous functions of the body. Analysis of electrolytes such as sodium and potassium are performed in the traditional clinical chemistry laboratory, but are...

Point-of-care testing provides rapid laboratory diagnostics close to the site of care. Quality assurance of POCT, however, requires significant resources that should be matched with improved patient outcome and benefit. Application of evidence-based medicine to POCT can critically assess the medical effectiveness of...

Children are not just small adults, and present unique challenges to the clinical laboratory. Blood specimens must be very small; for example, total blood volumes in a premature infant can be as small as 115 mL. Genetic diseases frequently must be detected in the newborn period. Reference values change with age....

The application of transcutaneous pO₂/pCO₂ monitoring is essential in optimizing the ventilatory management of critically ill newborns. Application areas include high-frequency oscillatory ventilation initiation, transitioning modes of ventilation, and inter-facility transport.

Electronic fetal monitoring (EFM) during labor has been performed for 40 years. However, the specificity in diagnosing asphyxia is still insufficient. The combination of EFM and fetal scalp-blood sampling was introduced shortly after the introduction of EFM.  Although this monitoring ensures a better sensitivity and...

How do small labs cope with the demands of modern quality assurance? In this interview, Ruth Lock, head of the laboratory of the Anesthesiology and Intensive Care Dept. of the Copenhagen County Hospital in Glostrup, Denmark, tells how her lab keeps up with demands with the help of training and quality control.