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Articles by James H. Nichols
Showing articles by "James H. Nichols"
Article
January 2011
Critical values in laboratory medicine
The process of patient sample testing, whether performed in the clinical laboratory or at the point of care, is the sum of three distinct phases. The first is the preanalytical phase, which includes test selection as well as sample collection and handling.
The second is the analytical or measuring phase that...
Bilirubin
Electrolytes
Point-of-care testing
Blood gases/acid-base
Glucose
Lactate
Creatinine/urea
Hemoglobins
Kidneys/fluids
Article
October 2010
D-dimer: Past, present, and future
The following is a copy of an article from Nursing 2007, Fall 2007 Volume 37 Number 8 - Supplement: ED Insider, Pages 14 - 16
The D-dimer level is a measure of clot formation and lysis that results from the degradation of cross-linked fibrin. Widely used as an indicator for the presence of disseminated intravascular ...
Coagulation/fibrinolysis
D-dimer
Article
October 2010
Creatinine measurement in the radiology department 2
Clinical laboratory measurement of serum/plasma creatinine concentration has been used to assess patient kidney function for well over 50 years.
With the incorporation of creatinine analyses to blood gas and other point-of-care platforms the test is now available outside the laboratory, at the bedside and in the...
Point-of-care testing
Glucose
Creatinine/urea
Article
July 2010
Diagnosis of DVT with D-dimer testing and the Wells score
The following is a copy of an article from Evidence-Based Practice, 2007; 10(12):1-2.
Venous thromboembolism refers to a spectrum of disease that includes both pulmonary embolus and deep-venous thrombosis (DVT).
More than 250,000 people in the United States are diagnosed annually with venous thromboembolic disease;...
Coagulation/fibrinolysis
D-dimer
Article
July 2010
Lean as a learning system in a hospital ward
PURPOSE – The purpose of this article is to discuss lean as a learning system in a hospital ward.
DESIGN/METHODOLOGY/APPROACH – Discusses lean as a learning system in a hospital ward.
FINDINGS – The Toyota veterans are fond of saying, lean is about “making people before making parts” or, in the wards’ context,...
Process optimization
Information management
Article
July 2010
Cardiac biomarkers for acute coronary syndrome and ongoing myocardial damage in heart failure
The growing role of cardiac markers has
been elucidated in patients with acute coronary syndrome, heart
failure and other cardiovascular diseases.
The markers can be cytosolic like
heart-type fatty-acid-binding protein (H-FABP) and creatine kinase
MB (CKMB), myofibrillary like troponin T (TnT) and cardio-endocrine...
Cardiac markers
Troponins
Natriuretic peptide
Article
April 2010
Creatinine measurement in the radiology department 1
Clinical laboratory measurement of serum/plasma creatinine concentration has been used to assess patient kidney function for well over 50 years. With incorporation of creatinine analyses to blood gas and other point-of-care platforms the test is now available outside the laboratory, at the bedside and in the clinic.
...
Point-of-care testing
Creatinine/urea
Kidneys/fluids
Article
April 2010
Can lean save lives
PURPOSE – The purpose of this paper is to show how over the last 18 months Bolton Hospitals NHS Trust have been exploring whether or not lean methodologies, often known as the Toyota Production System, can indeed be applied to healthcare.
DESIGN/METHODOLOGY/APPROACH – This paper is a viewpoint.
FINDINGS – One’s...
Process optimization
Information management
Article
January 2010
Interpretation of laboratory results
Clinical laboratory test results are a very important parameter in diagnosis, monitoring and screening. 70-80 % of decisions in diagnosis are based on laboratory results and more and more laboratory analyses are requested. Thus a lot of data are provided and it is therefore imperative for patient care (and safety)...
Information management
Glucose
Creatinine/urea
D-dimer
CRP
Article
January 2010
Blood oxygenation and spurious hypoxemia
One of the principal utilities of arterial blood gas
(ABG) analysis is to help assess blood oxygenation status. The two
ABG parameters used for this assessment are
pO2(a) (partial pressure of oxygen in arterial
blood) and sO2(a) (% of total hemoglobin that is
saturated with oxygen).
In health pO2(a) is
maintained...
Blood gases/acid-base
Point-of-care testing
Glucose
Hemoglobins
