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Articles by John G. Toffaletti
Showing articles by "John G. Toffaletti"
Article
April 2006
Red-cell transfusion – risks and benefits - part 2 of 2
This is the second of two articles about the risks and benefits of red-cell transfusion directed at healthcare professionals without any particular transfusion expertise.
The focus of the first article was the risks and the extensive measures taken to minimize those risks.
For this second article, attention turns to...
Blood gases/acid-base
Hemoglobins
Kidneys/fluids
Article
January 2006
The trouble with properly describing the oxygen-transport-related quantities
There is widespread confusion concerning the quantities to
be used in the description of the oxygen-transport properties of
human blood [1].
It all began in 1980 with the introduction of a
changed (and wrong) definition of oxygen saturation in a paper on a
new instrument for multicomponent analysis (MCA) of...
Blood gases/acid-base
Quality assurance
Hemoglobins
Article
January 2006
Red-cell transfusion – risks and benefits - part 1 of 2
Although often of life-saving benefit, transfusion of
donated red cells is associated with considerable potential risk
for the recipient patient.
This article, directed at healthcare
professionals without any particular transfusion expertise,
outlines these risks and the measures taken to minimize them.
Particular...
Blood gases/acid-base
Preanalytical phase
Hemoglobins
Neonatology
Article
January 2006
Neonatology - Get in control of fetal scalp blood sampling
Interview
Fetal scalp Blood Sampling (FBS) – not exactly wishful thinking for the mother, nor for the obstetrician? The procedure is regarded as cumbersome, the sample quality is questionable and the consequences of the result may be instrumental vaginal delivery or Cesarian Section (CS).
acutecaretesting.org has...
Preanalytical phase
Blood gases/acid-base
Neonatology
Lactate
Article
October 2005
Causes and clinical significance of increased carboxyhemoglobin
Hemoglobin is the oxygen-carrying protein contained in
red blood cells (erythrocytes). Although normally present in only
trace amounts, there are three species of hemoglobin that cannot
transport oxygen.
The three species, collectively called
dyshemoglobins because of their functional redundancy, are
methemoglobin,...
Blood gases/acid-base
Hemoglobins
Article
June 2005
Hemoglobin and its measurement
Methods for the measurement of hemoglobin (Hb) were first
developed well over a century ago, so that hemoglobin was among the
first diagnostic blood tests available to clinicians during the
first decades of the 20th century when laboratory medicine was in
its infancy.
Today it is the most frequently requested blood...
Preanalytical phase
Article
June 2005
Reducing sharps injury risk in intensive care
Five years of data on percutaneous injuries (PIs) from the EPINet multi-hospital sharps injury database at the University of Virginia were analyzed to understand exposure risks faced by personnel in intensive care/critical care settings.
Of 687 PIs in intensive care units (ICUs), nurses had the highest proportion of...
Quality assurance
Blood gases/acid-base
Preanalytical phase
Article
April 2005
Make document management user-friendly
In 1998, Fleury Diagnostics, Brazil's most comprehensive center for diagnostic medicine and pathology with 1,600 employees and 2,500 patients a day, implemented its own system for managing documents necessary for certification and point-of-care testing (POCT) programs. The system was entirely developed in-house in the ...
Process optimization
Information management
Article
April 2005
Behind the glucose protocol
In 2001, Belgian professor Greet Van den Berghe, PhD, and her colleagues at the Leuven University Hospital began a small revolution with the publication of the 2001 study “Intensive insulin therapy in critically ill patients”.
According to the study, tighter glucose control based on insulin therapy lowered rates of...
Glucose
Point-of-care testing
Article
April 2005
Management of neonatal hyperbilirubinemia
Supported by Pennsylvania Hospital Kernicterus Fund and the Eglin Fund
In the late 1980s, the question whether bilirubin damaged the brain of healthy infants was unanswered. The absence of documented evidence influenced the formulation of the 1994 consensus-based guidelines...
Neonatology
Bilirubin
