Patients with heart failure (HF) experience significant morbidity and mortality and those admitted for acute decompensated HF are at particularly high risk for adverse events. Hospitalization represents the major component of the high cost associated with the management of patients with HF. Accordingly, early and...

The discriminative ability of a diagnostic procedure is called diagnostic accuracy, and a number of quantitative measures out of which sensitivity and specificity are mostly used in the biomedical literature can express it. Each diagnostic-accuracy measure relates to some specific aspects of a diagnostic procedure....

Recent studies of D-dimer as a “rule-out” test for deep venous thrombosis (DVT) frequently have used duplex ultrasound rather than venography as the gold standard. Because duplex ultrasound has limited ability to image the calf veins, there is potential for ultrasound studies to classify patients with calf DVT as...

Timely and accurate diagnosis of sepsis is of great importance for the choice of treatment, level of monitoring and prognosis. For this biomarkers could be a significant aid, and thus the search for and application of sepsis biomarkers are of great importance.  Current evidence suggests that C-reactive protein and...

In an exclusive acutecaretesting.org interview, Dr Mario Plebani, Head of the Department of Laboratory Medicine at the University Hospital of Padova, Italy and international patient safety advocate, talks about how laboratory, clinicians and manufacturers can work together to reduce errors in testing and diagnosing...

With the use of a new Data Management System (DMS) software program [1], the majority of Point Of Care Testing (POCT) equipment throughout the Waikato District Health Board region has been connected to the Laboratory Information System (LIS) and the Hospital Information System (HIS). Prior to the new DMS, viewing...

Introduction of point–of-care testing (POCT) in hospitals requires the use of principles of change management. Manufacturers can support this process. E-learning programs adapted to the local situation with regular updates, a centralized accreditation and user-registration system and service level agreements are...

Maintaining lasting progress in laboratory test utilization is difficult to do without a reminder tool for providers. Since implementation of a quarterly physician report card in 2003, we have seen sustained improvement in the ordering of wellness tests in an ambulatory care network in the United States for over four...

Reprinted from AMERICAN JOURNAL OF CRITICAL CARE, November 2006, Volume 15, No 6, 595-599 Hudson TL, Dukes SF, Reilly K. Use of local anesthesia for arterial puncture. Copyright with permission from American Journal of Critical Care BACKGROUND Except for intravenous therapy, arterial access is the most common...

Modern analytical devices for testing biological fluids, such as blood, have now developed a sophistication that ensures the quality of the analytical result is capable of matching that achieved in the central laboratory.    Complementary developments are focused on reducing operator-related and connectivity-related...