Supported by Pennsylvania Hospital Kernicterus Fund and the Eglin Fund In the late 1980s, the question whether bilirubin damaged the brain of healthy infants was unanswered. The absence of documented evidence influenced the formulation of the 1994 consensus-based guidelines...

What does it take to ensure an effective competency program? Acutecaretesting.org asked three point-of-care coordinators (POCC) with solid programs what makes their competencies work. Their input resulted in a list of 12 key recommendations.

Is it a good idea to rely on vendors to help develop training materials for point-of-care testing staff? According to the lab group responsible for point-of-care (POC) testing at the Malmö University Hospital in Sweden, vendor cooperation can help you achieve a better result, faster. However, the better prepared you ...

Test results are commonly interpreted against population-based reference (normal) intervals, which should be provided on every laboratory report, irrespective of whether the test has been done as point-of-care testing or in a clinical laboratory. Reference intervals are difficult to generate properly if international ...

About half of all newborn infants born at term develop jaundice during their first days of life, and the lower the gestational age the more frequent the jaundice is. Newborns develop hyperbilirubinemia because of a large bilirubin production, low hepatic excretion and enterohepatic recirculation. At birth the newborn ...

A specimen for clinical laboratory testing must be properly collected from the correct patient at the correct time with proper patient preparation, and the right test must be performed for answering the right question. Quality in the preanalytical phase of laboratory activity can be assured by implementing a quality...

Biochemical and hematological analyses are done in laboratories, clinics, general practices and in point-of-care settings such as ITU.  Generally, numerical test results are generated.   Test results vary in individuals over time due to preanalytical variation, analytical imprecision and biological variation. The...

Point-of-care testing (POCT) is one of the most rapidly growing areas within laboratory medicine. The need for POCT has developed because in many cases the central laboratory has been unable to meet the expectations of clinical users, particularly with respect to turnaround time. It is widely recognized that...

Arterial blood gas analysis with the measurement of the partial pressure of carbon dioxide in arterial blood may be performed in the Pediatric ICU to evaluate the efficacy of ventilation or evaluate acid-base status. Although the direct measurement of PaCO₂ remains the gold standard, it provides only a single...

Oxygen saturation can be obtained from many different types of devices. This range of choices causes some confusion as to definitions of measured variables and their clinical interpretation. This article gives some historical background and describes the two different ways saturation can be obtained from a blood gas ...