The principal function of the protein hemoglobin contained in red blood cells is transport of oxygen in inspired air from lungs to tissue cells. Although normally present in only trace amounts, there are three species of hemoglobin that cannot transport oxygen. The three species, collectively called the dyshemoglobins ...

What does it take to create and maintain a quality point-of-care program in a world-renowned healthcare institution? acutecaretesting.org recently asked that question to Paula Santrach, MD, Interim Chair of the Dept. of Laboratory Medicine and Pathology at the Mayo Clinic in the US. She came back with a list* of 10...

Reprinted with permission from British Journal of Nursing, 2004, Vol 13, No 9.  Arterial puncture is the most common method used to obtain a sample for the measurement of arterial blood gases (ABGs) and is essential to guide the prescription of long-term oxygen therapy (LTOT) in patients with chronic hypoxic lung...

The National Academy of Clinical Biochemistry has developed a Laboratory Medicine Practice Guideline for point-of-care testing (POCT). This POCT guideline systematically reviews the scientific literature linking POCT to patient outcome and makes recommendations for the optimal use of POCT in patient care.  This...

The National Kidney Disease Education Program (NKDEP) Laboratory Working Group reviewed problems related to serum creatinine measurement for estimating glomerular filtration rate (GFR) and prepared recommendations to standardize and improve creatinine measurement. The NKDEP recommends using the estimating equation...

This is the second of two articles about the risks and benefits of red-cell transfusion directed at healthcare professionals without any particular transfusion expertise. The focus of the first article was the risks and the extensive measures taken to minimize those risks. For this second article, attention turns to...

Although often of life-saving benefit, transfusion of donated red cells is associated with considerable potential risk for the recipient patient. This article, directed at healthcare professionals without any particular transfusion expertise, outlines these risks and the measures taken to minimize them. Particular...

Reprinted with permission from Elsevier from "Neonate capillary blood gas reference values", by Jocelyne Cousineau, Suzanne Anctil, Ana Carceller, Monique Gonthier and Edgard E. Delvin, CLINICAL BIOCHEMISTRY, Vol no 38, 2005, pp 905-907. Copyright 2005 by Canadian Society of Clinical Chemists. OBJECTIVES Because...

Laboratorians need to take ownership of errors, identifying, analyzing and reducing them, thereby increasing patient safety. A Client Services Department, customer care representatives, a service improvement coordinator, “morning report”, electronic error tracking and reporting mechanisms, point-of-care support...

Hemoglobin is the oxygen-carrying protein contained in red blood cells (erythrocytes). Although normally present in only trace amounts, there are three species of hemoglobin that cannot transport oxygen.  The three species, collectively called dyshemoglobins because of their functional redundancy, are methemoglobin,...