This is the third in a series of four essays on www.acutecaretesting.org.  The first essay, "Quality control in theory and practice – a gap analysis", raised the question: Has “the system” given front-line laboratory workers the knowledge and tools they need to make quality control decisions wisely? Or is there a...

In Geneva in 1821, a French nobleman Jacques Alexandre Le Jumeau, Vicomte de Kergaradec, became the pioneer of modern fetal monitoring. He described the sound of the fetal heartbeat, as he used the newly invented stethoscope (by Laennec, France 1819) and applied it to the abdominal wall of a pregnant woman [1]. The...

Although creatinine clearance has been the mainstay for estimating glomerular filtration rate (GFR) in laboratories for the past half-century, prediction equations based on serum creatinine and other routine serum analytes are now available which enable reporting of a calculated GFR using the Modification of Diet in...

As point-of-care testing (POCT) continues to expand in the hospital environment, the desire of physicians to participate in the performance of testing may increase. This article discusses the required competencies for a physician who wishes to be involved in laboratory testing and some practical considerations for...

The National Academy of Clinical Biochemistry has developed a Laboratory Medicine Practice Guideline for point-of-care testing (POCT). This POCT guideline systematically reviews the scientific literature linking POCT to patient outcome and makes recommendations for the optimal use of POCT in patient care.  This...

This is the second in a series of articles. The first essay, “Quality control in theory and practice – a gap analysis”, published here in January 2006 raised the question: Has “the system” given front-line laboratory workers the knowledge and tools they need to make quality control decisions wisely – or is there a...

The National Kidney Disease Education Program (NKDEP) Laboratory Working Group reviewed problems related to serum creatinine measurement for estimating glomerular filtration rate (GFR) and prepared recommendations to standardize and improve creatinine measurement. The NKDEP recommends using the estimating equation...

This is the second of two articles about the risks and benefits of red-cell transfusion directed at healthcare professionals without any particular transfusion expertise. The focus of the first article was the risks and the extensive measures taken to minimize those risks. For this second article, attention turns to...

Millions of times every day, in a myriad of distinctive laboratories around this globe, front-line workers make the final decision on the quality of results they report. If they decide the quality is “OK”, patient results are released to impact clinical decisions, and proficiency values reflect the overall ability...

There is widespread confusion concerning the quantities to be used in the description of the oxygen-transport properties of human blood [1]. It all began in 1980 with the introduction of a changed (and wrong) definition of oxygen saturation in a paper on a new instrument for multicomponent analysis (MCA) of...