Apgar scores and umbilical artery pH have traditionally been used as objective measures of neonatal asphyxia. According to the literature, the practice of cord gas analysis varies greatly both between and within countries - whether analysis is performed, whether it is routine at all births and why it is performed...

The understanding and management of ventilation-perfusion (V/Q) relationships represents a cornerstone of intensive care unit (ICU) patient management.  The physiologic shunt calculation can reliably reflect the degree of gas exchange attributable to intrapulmonary disease or intracardiac shunting regardless of other ...

Cord blood ph measurement at birth, using relatively simple and non-invasive methods, provides obstetricians and perinatologists with an objective and sensitive measure for the condition of the infant during the final stage of birth.  As long as certain criteria are observed, the reported values are reliable. Routine ...

In the U.S. all clinical laboratory determinations, including blood gas testing performed at point of care (POC) or in the central laboratory, is regulated by the Clinical Laboratory Improvement Amendments of 1988 (CLIA).  Congress passed CLIA to ensure accurate, reliable, and timely test results regardless of...

When it comes to acid base, there is no getting around the name of Ole Siggaard-Andersen (OSA). acutecaretesting.org talks to the world-renowned Danish professor, who has become a legend in the field of blood gas.

Fluid and electrolyte management is an important and challenging part of the management of any very premature or critically ill newborn. The newborn's ability to maintain fluid and electrolyte homeostasis in the face of the vagaries of extrauterine life is compromised by immature renal function. The very premature...

External Quality Assessment (EQA) in medical laboratories have evolved over the past 50 years to provide more sophisticated systems compared with the simple participants’ analytical performance evaluation of earlier years.  There are clear distinctions between the proficiency testing schemes and the evolved External...

Monitoring of blood gases is essential in neonatal intensive care. Traditionally arterial samples have been considered the gold standard, but in critically ill neonates physiological changes can happen within minutes to a degree endangering the newborn. Clinicians can therefore not rely solely on intermittent...

That is the question the Hvidovre Hospital had to ask itself in May 2003, when the Danish National Board of Health and the Copenhagen Hospital Corporation appointed it to be one of the country's three key sites for receiving and treating SARS patients. Once appointed, the hospital began a painstaking process of...

Danish neonatal intensive care units (NICUs) are known throughout the world for practicing minimal handling. Because it is non-invasive, transcutaneous monitoring of pO₂ and pCO₂ plays an important role in this setup. acutecaretesting.org has interviewed Professor Gorm Greisen, MD, Dr. Med. Sci., and Head of the...