How do small labs cope with the demands of modern quality assurance? In this interview, Ruth Lock, head of the laboratory of the Anesthesiology and Intensive Care Dept. of the Copenhagen County Hospital in Glostrup, Denmark, tells how her lab keeps up with demands with the help of training and quality control.

60 % of all neonates develop jaundice during their first week of life and thereby run a risk of getting hyperbilirubinemia.  Although different approaches for establishing treatment criteria have been suggested, treatment of neonatal hyperbilirubinemia is usually still based on the measurement of total bilirubin...

Two months of acclimatization to high altitude leads to an adaptation of the aerobic capacity of the myocardium, characterized by an increased ability to extract O₂ from the coronary vascular bed. An increased mitochondrial volume and activity of oxidative enzymes or improved diffusion conditions could be involved.

Providing continuous technical support and reliable test data collection for point-of-care blood gas testing is a difficult task for many laboratories.  Here we describe how the implementation of an integrated instrument control and data management system for point-of-care blood gas testing has streamlined these...

Examination of peripheral pulses and peripheral blood pressures are commonly used methods for investigation of macrocirculation. However, falsely elevated peripheral blood pressures may complicate the accurate prediction of ulcer healing in diabetic patients.  Because tcpO₂ also measures the nutritive skin capillary...

The pro-con debate on the advisability of introducing POCT deals with the likely clinical benefits but – to an even higher degree – with the economic aspects. We discuss various models for determining the costs, and some caveats.

The effects of carbon monoxide poisoning have been found to be greatly alleviated, or in some cases eliminated, through the use of hyperbaric oxygen therapy. This paper discusses the pathophysiology of carbon monoxide intoxication and presents an overview of its treatment.

Postoperative monitoring in critical care patients has become a widening field over the past few decades. Improvements in outcome can be related to advances in this field as well as in intraoperative management and preoperative assessment.

Measurement of transcutaneous oxygen tension (tcpO₂) has gained worldwide acceptance as a simple and effective method of evaluating cutaneous blood flow in settings where skin viability and the adequacy of skin blood flow are of major concern. An example of such a setting is the non-invasive vascular laboratory at...

Application of wound healing management algorithms in hyperbaric oxygen therapy improve clinical outcomes and, at the same time, markedly reduce expenditures.